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Much of the work we do in HIV prevention is aimed at trying to stop people from engaging in behaviours that could expose them to HIV and potentially lead to infection. But what happens if someone thinks they may have already been exposed to HIV? Is there a way we can stop them from getting infected? Post-exposure prophylaxis, or PEP, could be an option.h

What is post-exposure prophylaxis(PEP)?

With PEP, an HIV-negative person who may have been exposed to HIV takes anti-HIV drugs prescribed by a doctor to prevent infection. These are the same drugs that people living with HIV take. PEP involves taking two or three of these drugs for a period of one month. To effectively reduce a person’s risk of becoming HIV-positive, PEP must be taken within 72 hours of possible exposure to HIV but ideally as early as possible. In the world of PEP, exposure to HIV is often divided into two categories: occupational exposure and non-occupational exposure. “Occupational” exposure refers to exposure to HIV at work, in a healthcare setting. For example, a healthcare provider could be exposed to HIV through a needlestick injury at work. “Non-occupational” exposure refers to exposure to HIV through sex or drug use, for example, when a person shares a needle or has sex without a condom.